Methylphenidate-associated myopathy

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Methylphenidate-associated myopathy

Methods We describe a case of a 13 yo girl diagnosed with ADHD since early childhood, in MP use for the past 3 years. She complained about a mild discomfort of proximal muscles of the lower limbs and cramps for the previous 3 months. Routine exams revealed increased aminotransferases levels (AST 192 UI/L; ALT 222 UI/L), suggesting hepatotoxicity. New laboratory tests were ordered, showing a CPK...

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Cardiomyopathic findings associated with methylphenidate.

Cardiomyopathic findings associated with methylphenidate.

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Familial visceral myopathy associated with a mitochondrial myopathy.

A 27 year old man with intestinal pseudo-obstruction who developed parenteral nutrition induced hyperlipidaemia and who also had ophthalmoplegia and an undifferentiated myopathy is described. Histological examination of biopsy specimens and molecular analysis show that this patient had both familial visceral myopathy and a mitochondrial myopathy, suggesting that a mitochondrial DNA mutation is ...

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Methylphenidate (Ritalin)-associated cataract and glaucoma.

Methylphenidate hydrochloride (Ritalin) is the drug of choice for attention deficit hyperactivity disorder (ADHD). However, an association of Ritalin with glaucoma has been reported. We report a case of Ritalin-associated cataract and glaucoma. A 10-year-old boy was diagnosed with ADHD and had received methylphenidate hydrochloride, 60 mg/day for 2 years. He presented with blurred vision. Best-...

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Lacunar stroke associated with methylphenidate abuse.

BACKGROUND Methylphenidate is a central nervous system stimulant used for the treatment of attention deficit hyperactivity disorder and narcolepsy and like other psychostimulants has a potential for abuse. CASE STUDY A young man with a cerebral lacunar infarction following chronic oral abuse of methylphenidate is presented. CONCLUSIONS The experience of our patient and a review of the liter...

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ژورنال

عنوان ژورنال: Pediatric Rheumatology

سال: 2012

ISSN: 1546-0096

DOI: 10.1186/1546-0096-10-s1-a96